NAD+: Cellular Energy and Longevity Peptide Research

NAD+ (nicotinamide adenine dinucleotide), while technically a coenzyme, is researched alongside peptides for cellular energy, DNA repair, and longevity pathways.

NAD+ Research Highlights

Mitochondrial function restoration in aging models by David A. Sinclair at Harvard Medical School showed 20% ATP increase. Sirtuin activation for DNA repair per Leonard Guarente at MIT.

Neuroprotection in Parkinson's models by Vilhelm A. Bohr at the National Institute on Aging. Cardiovascular benefits via PARP modulation by Jun Ren at the University of Wyoming.

NAD+ Mechanisms

Electron carrier in redox reactions; substrate for sirtuins, PARPs, and CD38. Levels decline ~50% by age 50.

NAD+ Research Directions

NMN/NR precursor comparisons by Charles Brenner at the University of Iowa. IV NAD+ pharmacokinetics by Ross Grant at the University of Sydney.

Links

• [Sinclair](https://pubmed.ncbi.nlm.nih.gov/24360282/)
• [Guarente](https://pubmed.ncbi.nlm.nih.gov/10224252/)