Sermorelin: GHRH Analog Peptide Research Developments

Sermorelin, a 29-amino acid GHRH analog, stimulates endogenous GH secretion in aging and deficiency models. Research from Gerontology Research Center and Endocrine Society.

Sermorelin Research Updates

Sarcopenia mitigation in elderly models by Robert S. Tan at the University of Texas showed 12% lean mass gains over 6 months. Sleep architecture improvements per John Morley at Saint Louis University enhanced slow-wave sleep by 20%.

Fat redistribution in HIV lipodystrophy by Kenneth H. Mayer at Fenway Health. Bone turnover markers increased in osteopenia models by Michael Kleerekoper at Wayne State University.

Sermorelin Action Mechanisms

GHRH receptor binding on somatotrophs triggers cAMP signaling, as in Endocrine Reviews by Christian J. Strasburger at Charité Berlin. Pulsatile release mimics physiological rhythms.

IGF-1 elevation in deficiency models by Ron G. Rosenfeld at Stanford University.

Future Sermorelin Directions

Combination with GHRP-6 by Richard F. Walker at the University of South Florida. Oral formulation development by Aegis Sciences Corporation.

Links

• [Sarcopenia](https://pubmed.ncbi.nlm.nih.gov/12507632/)
• [Sleep](https://pubmed.ncbi.nlm.nih.gov/9620571/)